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KLK5 |激肽释放酶5

KLK5 | Kallikrein 5

人激肽释放酶5(KLK 5)是以其无活性形式产生的丝氨酸蛋白酶。它以催化活性形式存在于角质层中。据报道,它降解桥粒/角桥粒,表明它参与脱屑。Egelrud等人(2005)hK 5和hK 7,两种人类皮肤中丰富的丝氨酸蛋白酶,被LEKTI结构域6抑制。皮肤病学研究杂志,124(1):198- 203.别名:角质层胰蛋白酶,激肽释放酶样蛋白2,KLK-L2

货号:AS06-102品牌:Agrisera 规格:200ul价格:询价元 说明书:点击查看 COA下载:点击查看

背景资料


Human Kallikrein 5 (KLK5) is a serine protease produced in its inactive form. It is found in catalytically active form in stratum corneum. It has been reported to degrade desmosomes/corneodesmosomes, suggesting that it is involved in desquamtion. Egelrud et al. (2005) hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6. J Invest Dermatol, 124(1):198-203.Alternative names: stratum corneum tryptic enzyme, Kallikrein-like protein 2, KLK-L2


应用类型


Western blot (WB)


免疫原


KLH-conjugated mix of two synthetic peptides: one chosen from C-terminal and the other one from midregion of human KLK5 Q9Y337


宿主



反应性


保存条件


Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

品牌介绍


Agrisera公司提供1000种用于植物和藻类细胞生物学研究的一抗,2000多种二抗。Agrisera公司提供的植物领域的抗体涵盖拟南芥、莱茵衣藻、蓝藻、松柏类、硅藻、大豆、大麦、蒺藜苜蓿、烟草、稻、菜豆、小立碗藓、杨树、豌豆、番茄、马铃薯、菠菜、小麦、玉米、葡萄等多个物种,此外还有水生生物类(藻类、鱼)抗体,细菌、昆虫、真菌抗体。针对植物蛋白质的保守氨基酸序列,Agirsera还独家开发了数十种通用抗体(global antibodies),这类抗体几乎可以与所有的高等植物及藻类产生免疫反应,可为研究人员提供极为方便的选择。

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