产品详情
噻唑烷二酮衍生物；5-（4-（2-（噻吩-2-基）乙氧基）亚苄基）噻唑烷-2,4-二酮 CAS:132539-06-1
Thiazolidinedione derivative; 5-(4-(2-(thiophen-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione
A TZD derivative that inhibits 15-PGDH activity with an IC50 value of 31 nM
背景资料
Prostaglandins have a short life in vivo because NAD+-dependent 15-hydroxy prostaglandin dehydrogenase (15-PGDH) catalyzes their oxidation to 15-keto metabolites with greatly reduced biological activity.{340} Thiazolidinediones (TZDs) are a class of PPARγ agonists that have potent 15-PGDH inhibitory activity.{10583,17925} CAY10638 is a TZD derivative that inhibits 15-PGDH activity with an IC50 value of 31 nM.{17925}
保存条件
建议您在收到Cayman Chemical品牌的CAY10638 (1 mg)产品后置于-20度保存，产品有效期为730天.
品牌介绍
Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.Cayman Chemical可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为Cayman Chemical在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Cayman Chemical产品以及客户订制化服务.
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